Reishi Mushroom Extract Ganoderma lucidum Treatment by Triterpenes

As we know that Triterpenes are chemical compounds composed of 3 terpene units. It is the combination with the molecular formula C30H48. It may be thought of consisting of 6 isoprene units. Plants, Animals, and fungi create triterpenes.
 
The triterpenes are the most numerous and diverse groups of the plant for producing natural products. These are complex molecules where we can get various types of medicines through chemical synthesis. Simple triterpenes are the components of specialized membranes, surface waxes and it may potentially act as signaling molecules. The complex glycosylated triterpenes provide extra protection against pests and pathogens. It has simple and conjugated triterpenes that have a wide range of applications in the health, food and industrial biotechnology sectors. Here, we get a review of recent developments in the sector of triterpene biosynthesis, provide an overview of the enzymes and genes that have been identified to date, and it discusses strategies for discovering a new triterpene biosynthetic pathways.
It is used for the following treatment, these are:
 
Cancers
In the present study of “Pentacyclic Triterpenes of the Lupane”, most of the researchers found in an abstract that triterpene monoalcohols and Triterpene acids show an antioxidative potential. Nowadays the number of cancer patients is increasing day by day in the world. It is difficult for physicians to treat all patients through traditional methods. According to the report of a medical journal, we can use the pharmacological potential of triterpenes for the treatment of oleanane or ursane type for cancer.  Although there is no clinical trial has been published by using these triterpenes in the cancer therapy. It provides a multitarget potential for new cancer strategies. It is an effective approach for cancer treatment that has to be proven. Because some triterpenes are utilizing the plant metabolites, now the utilization of different plants are the great sources of interest. Some Parts of plants such as rosemary leaves, mistletoe shoots, birch bark, apple peel are rich in triterpenes and it provides different triterpene compositions.
 
Treatment of Colon Cancer
According to the recent study of ” Triterpenes for Colon cancer” by Baldridge LA, Thyagarajan A, Jiang J, Terry C,  Jedinak A, and Nguyen H, Sliva D, they found triterpenes are suitable for the treatment of colon cancer.
 
Inflammatory response in our body
It is another great problem in our health.
In a current study of ” Suppression of the inflammatory response”  by Dudhgaonkar S and Thyagarajan A, Sliva D, posted in PubMed, most of the researchers found that it is Apart from its anti-inflammatory activity, which was mediated by down-regulation of cell cycle regulatory proteins cyclin CDK4, D1, and cyclin B1 respectively. The anti-inflammatory and the anti-proliferative effects are treated through the inhibition of AP-1  and NF-kappaB signaling pathways.
 
Treatment of Hepatoprotective
According to the new study of  “Hepatoprotective”  by Abdallah HM, Ezzat SM, El-Maraghy SA and Fawzy GA, posted in PubMed, some researchers found that it is used for the treatment of Hepatoprotective. It was assessed in the reduction in histological damage of our body. It was also accompanied by restoration of the aspartate aminotransferase (AST), nitric oxide (NO),  liver enzymes, lactate dehydrogenase (LDH), and a reduction in the inflammatory markers (tumor necrosis-α (TNF-α), myloperoxidase (MPO), N-acetyl-β-D-glucosaminidase (NAG) in serum.  It can restoration of the oxidant balance by decreasing hepatic malondialdehyde (MDA) levels and the serum, along with increasing the activity of glutathione peroxidase (GSHPx), hepatic catalase (CAT), and the non-enzymatic antioxidant glutathione (GSH).
 
Treatment of Breast Cancer
According to the report of a medical study of “ breast cancer cells”, it is used for Reduction of Wnt proteins and translocation of galectin-3-mediated β-catenin of the nucleus. Many researchers indicated the relative activities which were reduced when we treat cells with cucurbitacin B compound for a day. It suggests that may induce apoptosis and exert growth our inhibitory effect through interruption.
 
For the treatment HIV virus
In a recent study of “human immunodeficiency virus (HIV)”, many scientists found transcription and replication of  Molecular Immunology and Infectious Disease based on Molecular Toxicology in HIV.
They used biochemical techniques which were demonstrated by Cel. It is used for the treatment of HIV affected people. Nowadays many physicians like to use this for the treatment of HIV affected people. Thus it is a reliable treatment for the human being.